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Conformational and thermodynamic properties modulate the nucleotide excision repair of 2-aminofluorene and 2-acetylaminofluorene dG adducts in the NarI sequence
Nucleotide excision repair (NER) is a major repair pathway that recognizes and corrects various lesions in cellular DNA. We hypothesize that damage recognition is an initial step in NER that senses conformational anomalies in the DNA caused by lesions. We prepared three DNA duplexes containing the c...
Autores principales: | Jain, Vipin, Hilton, Benjamin, Patnaik, Satyakam, Zou, Yue, Chiarelli, M. Paul, Cho, Bongsup P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3351159/ https://www.ncbi.nlm.nih.gov/pubmed/22241773 http://dx.doi.org/10.1093/nar/gkr1307 |
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