Visualization of a DNA-PK/PARP1 complex

The DNA-dependent protein kinase (DNA-PK) and Poly(ADP-ribose) polymerase-1 (PARP1) are critical enzymes that reduce genomic damage caused by DNA lesions. They are both activated by DNA strand breaks generated by physiological and environmental factors, and they have been shown to interact. Here, we...

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Detalles Bibliográficos
Autores principales: Spagnolo, Laura, Barbeau, Jody, Curtin, Nicola J., Morris, Edward P., Pearl, Laurence H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3351162/
https://www.ncbi.nlm.nih.gov/pubmed/22223246
http://dx.doi.org/10.1093/nar/gkr1231

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3351162/
https://www.ncbi.nlm.nih.gov/pubmed/22223246
http://dx.doi.org/10.1093/nar/gkr1231

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