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Visualization of a DNA-PK/PARP1 complex
The DNA-dependent protein kinase (DNA-PK) and Poly(ADP-ribose) polymerase-1 (PARP1) are critical enzymes that reduce genomic damage caused by DNA lesions. They are both activated by DNA strand breaks generated by physiological and environmental factors, and they have been shown to interact. Here, we...
Autores principales: | Spagnolo, Laura, Barbeau, Jody, Curtin, Nicola J., Morris, Edward P., Pearl, Laurence H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3351162/ https://www.ncbi.nlm.nih.gov/pubmed/22223246 http://dx.doi.org/10.1093/nar/gkr1231 |
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