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Complex activities of the human Bloom's syndrome helicase are encoded in a core region comprising the RecA and Zn-binding domains

Bloom's syndrome DNA helicase (BLM), a member of the RecQ family, is a key player in homologous recombination (HR)-based error-free DNA repair processes. During HR, BLM exerts various biochemical activities including single-stranded (ss) DNA translocation, separation and annealing of complement...

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Detalles Bibliográficos
Autores principales: Gyimesi, Máté, Harami, Gábor M., Sarlós, Kata, Hazai, Eszter, Bikádi, Zsolt, Kovács, Mihály
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3351180/
https://www.ncbi.nlm.nih.gov/pubmed/22253018
http://dx.doi.org/10.1093/nar/gks008