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Base methylations in the double-stranded RNA by a fused methyltransferase bearing unwinding activity

Modifications of rRNAs are clustered in functional regions of the ribosome. In Helix 74 of Escherichia coli 23S rRNA, guanosines at positions 2069 and 2445 are modified to 7-methylguanosine(m(7)G) and N(2)-methylguanosine(m(2)G), respectively. We searched for the gene responsible for m(7)G2069 forma...

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Detalles Bibliográficos
Autores principales: Kimura, Satoshi, Ikeuchi, Yoshiho, Kitahara, Kei, Sakaguchi, Yuriko, Suzuki, Takeo, Suzuki, Tsutomu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3351187/
https://www.ncbi.nlm.nih.gov/pubmed/22210896
http://dx.doi.org/10.1093/nar/gkr1287