Effects of Friedreich's ataxia GAA repeats on DNA replication in mammalian cells

Friedreich's ataxia (FRDA) is a common hereditary degenerative neuro-muscular disorder caused by expansions of the (GAA)n repeat in the first intron of the frataxin gene. The expanded repeats from parents frequently undergo further significant length changes as they are passed on to progeny. Ex...

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Detalles Bibliográficos
Autores principales: Chandok, Gurangad S., Patel, Mayank P., Mirkin, Sergei M., Krasilnikova, Maria M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3351192/
https://www.ncbi.nlm.nih.gov/pubmed/22262734
http://dx.doi.org/10.1093/nar/gks021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3351192/
https://www.ncbi.nlm.nih.gov/pubmed/22262734
http://dx.doi.org/10.1093/nar/gks021

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