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Duplications of the Neuropeptide Receptor VIPR2 Confer Significant Risk for Schizophrenia

Rare copy number variants (CNVs) play a prominent role in the etiology of schizophrenia and other neuropsychiatric disorders(1). Substantial risk for schizophrenia is conferred by large (>500 kb) CNVs at several loci, including microdeletions at 1q21.1 (2), 3q29 (3), 15q13.3 (2) and 22q11.2 (4) a...

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Detalles Bibliográficos
Autores principales: Vacic, Vladimir, McCarthy, Shane, Malhotra, Dheeraj, Murray, Fiona, Chou, Hsun-Hua, Peoples, Aine, Makarov, Vladimir, Yoon, Seungtai, Bhandari, Abhishek, Corominas, Roser, Iakoucheva, Lilia M., Krastoshevsky, Olga, Krause, Verena, Larach-Walters, Verónica, Welsh, David K., Craig, David, Kelsoe, John R., Gershon, Elliot S., Leal, Suzanne M., Aquila, Marie Dell, Morris, Derek W., Gill, Michael, Corvin, Aiden, Insel, Paul A., McClellan, Jon, King, Mary-Claire, Karayiorgou, Maria, Levy, Deborah L., DeLisi, Lynn E., Sebat, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3351382/
https://www.ncbi.nlm.nih.gov/pubmed/21346763
http://dx.doi.org/10.1038/nature09884