Plasticity of Adult Human Pancreatic Duct Cells by Neurogenin3-Mediated Reprogramming

AIMS/HYPOTHESIS: Duct cells isolated from adult human pancreas can be reprogrammed to express islet beta cell genes by adenoviral transduction of the developmental transcription factor neurogenin3 (Ngn3). In this study we aimed to fully characterize the extent of this reprogramming and intended to i...

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Detalles Bibliográficos
Autores principales: Swales, Nathalie, Martens, Geert A., Bonné, Stefan, Heremans, Yves, Borup, Rehannah, Van de Casteele, Mark, Ling, Zhidong, Pipeleers, Daniel, Ravassard, Philippe, Nielsen, Finn, Ferrer, Jorge, Heimberg, Harry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3351393/
https://www.ncbi.nlm.nih.gov/pubmed/22606327
http://dx.doi.org/10.1371/journal.pone.0037055

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3351393/
https://www.ncbi.nlm.nih.gov/pubmed/22606327
http://dx.doi.org/10.1371/journal.pone.0037055

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