The Tyrphostin Agent AG490 Prevents and Reverses Type 1 Diabetes in NOD Mice

BACKGROUND: Recent studies in the NOD (non-obese diabetic) mouse model of type 1 diabetes (T1D) support the notion that tyrosine kinase inhibitors have the potential for modulating disease development. However, the therapeutic effects of AG490 on the development of T1D are unknown. MATERIALS AND MET...

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Detalles Bibliográficos
Autores principales: Davoodi-Semiromi, Abdoreza, Wasserfall, Clive H., Xia, Chang Qing, Cooper-DeHoff, Rhonda M., Wabitsch, Martin, Clare-Salzler, Michael, Atkinson, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3351395/
https://www.ncbi.nlm.nih.gov/pubmed/22615750
http://dx.doi.org/10.1371/journal.pone.0036079

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3351395/
https://www.ncbi.nlm.nih.gov/pubmed/22615750
http://dx.doi.org/10.1371/journal.pone.0036079

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