Transgenic Expression of Nonclassically Secreted FGF Suppresses Kidney Repair

FGF1 is a signal peptide-less nonclassically released growth factor that is involved in angiogenesis, tissue repair, inflammation, and carcinogenesis. The effects of nonclassical FGF export in vivo are not sufficiently studied. We produced transgenic mice expressing FGF1 in endothelial cells (EC), w...

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Detalles Bibliográficos
Autores principales: Kirov, Aleksandr, Duarte, Maria, Guay, Justin, Karolak, Michele, Yan, Cong, Oxburgh, Leif, Prudovsky, Igor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3351418/
https://www.ncbi.nlm.nih.gov/pubmed/22606265
http://dx.doi.org/10.1371/journal.pone.0036485

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3351418/
https://www.ncbi.nlm.nih.gov/pubmed/22606265
http://dx.doi.org/10.1371/journal.pone.0036485

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