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Pph3 Dephosphorylation of Rad53 Is Required for Cell Recovery from MMS-Induced DNA Damage in Candida albicans

The pathogenic fungus Candida albicans switches from yeast growth to filamentous growth in response to genotoxic stresses, in which phosphoregulation of the checkpoint kinase Rad53 plays a crucial role. Here we report that the Pph3/Psy2 phosphatase complex, known to be involved in Rad53 dephosphoryl...

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Detalles Bibliográficos
Autores principales: Wang, Haitao, Gao, Jiaxin, Li, Wanjie, Wong, Ada Hang-Heng, Hu, Kangdi, Chen, Kun, Wang, Yue, Sang, Jianli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3351423/
https://www.ncbi.nlm.nih.gov/pubmed/22606354
http://dx.doi.org/10.1371/journal.pone.0037246