Sphingosine-1-Phosphate Enhances Satellite Cell Activation in Dystrophic Muscles through a S1PR2/STAT3 Signaling Pathway

Sphingosine-1-phosphate (S1P) activates a widely expressed family of G protein-coupled receptors, serves as a muscle trophic factor and activates muscle stem cells called satellite cells (SCs) through unknown mechanisms. Here we show that muscle injury induces dynamic changes in S1P signaling and me...

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Detalles Bibliográficos
Autores principales: Loh, Kenneth C., Leong, Weng-In, Carlson, Morgan E., Oskouian, Babak, Kumar, Ashok, Fyrst, Henrik, Zhang, Meng, Proia, Richard L., Hoffman, Eric P., Saba, Julie D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3351440/
https://www.ncbi.nlm.nih.gov/pubmed/22606352
http://dx.doi.org/10.1371/journal.pone.0037218

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3351440/
https://www.ncbi.nlm.nih.gov/pubmed/22606352
http://dx.doi.org/10.1371/journal.pone.0037218

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