Molecular Evolution of a Peptide GPCR Ligand Driven by Artificial Neural Networks

Peptide ligands of G protein-coupled receptors constitute valuable natural lead structures for the development of highly selective drugs and high-affinity tools to probe ligand-receptor interaction. Currently, pharmacological and metabolic modification of natural peptides involves either an iterativ...

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Detalles Bibliográficos
Autores principales: Bandholtz, Sebastian, Wichard, Jörg, Kühne, Ronald, Grötzinger, Carsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3351444/
https://www.ncbi.nlm.nih.gov/pubmed/22606313
http://dx.doi.org/10.1371/journal.pone.0036948

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3351444/
https://www.ncbi.nlm.nih.gov/pubmed/22606313
http://dx.doi.org/10.1371/journal.pone.0036948

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