Dihydrotestosterone Ameliorates Degeneration in Muscle, Axons and Motoneurons and Improves Motor Function in Amyotrophic Lateral Sclerosis Model Mice

Amyotrophic lateral sclerosis (ALS) is a lethal disease characterized by a progressive loss of motoneurons. The clinical symptoms include skeletal muscle weakness and atrophy, which impairs motor performance and eventually leads to respiratory failure. We tested whether dihydrotestosterone (DHT), wh...

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Detalles Bibliográficos
Autores principales: Yoo, Young-Eun, Ko, Chien-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3351454/
https://www.ncbi.nlm.nih.gov/pubmed/22606355
http://dx.doi.org/10.1371/journal.pone.0037258

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3351454/
https://www.ncbi.nlm.nih.gov/pubmed/22606355
http://dx.doi.org/10.1371/journal.pone.0037258

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