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Comprehensive analysis of published phase I/II clinical trials between 1990-2010 in osteosarcoma and Ewing sarcoma confirms limited outcomes and need for translational investment

BACKGROUND: High grade primary bone sarcomas are rare cancers that affect mostly children and young adults. Osteosarcoma and Ewing sarcoma are the most common histological subtypes in this age group, with current multimodality treatment strategies achieving 55-70% overall survival. As there remains...

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Detalles Bibliográficos
Autores principales: van Maldegem, Annemiek M, Bhosale, Aparna, Gelderblom, Hans J, Hogendoorn, Pancras CW, Hassan, Andrew B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3351714/
https://www.ncbi.nlm.nih.gov/pubmed/22587841
http://dx.doi.org/10.1186/2045-3329-2-5