Cargando…

The expression of spinal methyl-CpG-binding protein 2, DNA methyltransferases and histone deacetylases is modulated in persistent pain states

BACKGROUND: DNA CpG methylation is carried out by DNA methyltransferases and induces chromatin remodeling and gene silencing through a transcription repressor complex comprising the methyl-CpG-binding protein 2 (MeCP2) and a subset of histone deacetylases. Recently, we have found that MeCP2 activity...

Descripción completa

Detalles Bibliográficos
Autores principales: Tochiki, Keri K, Cunningham, Joel, Hunt, Stephen P, Géranton, Sandrine M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3351747/
https://www.ncbi.nlm.nih.gov/pubmed/22369085
http://dx.doi.org/10.1186/1744-8069-8-14