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Clopidogrel and proton pump inhibitor (PPI) interaction: separate intake and a non-omeprazole PPI the solution?

BACKGROUND: Dual therapy with aspirin and clopidogrel increases the risk of gastrointestinal bleeding. Therefore, co-therapy with a proton pump inhibitor (PPI) is recommended by most guidelines. However, there are warnings against combining PPIs with clopidogrel because of their interactions with cy...

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Detalles Bibliográficos
Autores principales: Kenngott, S, Olze, R, Kollmer, M, Bottheim, H, Laner, A, Holinski-Feder, E, Gross, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3352012/
https://www.ncbi.nlm.nih.gov/pubmed/20562062
http://dx.doi.org/10.1186/2047-783X-15-5-220