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Inhibition of SLPI ameliorates disease activity in experimental autoimmune encephalomyelitis

BACKGROUND: The secretory leukocyte protease inhibitor (SLPI) exerts wide ranging effects on inflammatory pathways and is upregulated in EAE but the biological role of SLPI in EAE, an animal model of multiple sclerosis is unknown METHODS: To investigate the pathophysiological effects of SLPI within...

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Detalles Bibliográficos
Autores principales: Müller, André Michael, Jun, Esther, Conlon, Hana, Sadiq, Saud Ahmed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3352067/
https://www.ncbi.nlm.nih.gov/pubmed/22436018
http://dx.doi.org/10.1186/1471-2202-13-30