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The reverse, but coordinated, roles of Tor2 (TORC1) and Tor1 (TORC2) kinases for growth, cell cycle and separase-mediated mitosis in Schizosaccharomyces pombe

Target of rapamycin complexes (TORCs), which are vital for nutrient utilization, contain a catalytic subunit with the phosphatidyl inositol kinase-related kinase (PIKK) motif. TORC1 is required for cell growth, while the functions of TORC2 are less well understood. We show here that the fission yeas...

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Detalles Bibliográficos
Autores principales: Ikai, Nobuyasu, Nakazawa, Norihiko, Hayashi, Takeshi, Yanagida, Mitsuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3352084/
https://www.ncbi.nlm.nih.gov/pubmed/22645648
http://dx.doi.org/10.1098/rsob.110007