Structure and function of FusB: an elongation factor G-binding fusidic acid resistance protein active in ribosomal translocation and recycling

Fusidic acid (FA) is a bacteriostatic antibiotic that locks elongation factor G (EF-G) to the ribosome after GTP hydrolysis during elongation and ribosome recycling. The plasmid pUB101-encoded protein FusB causes FA resistance in clinical isolates of Staphylococcus aureus through an interaction with...

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Detalles Bibliográficos
Autores principales: Guo, Xiaohu, Peisker, Kristin, Bäckbro, Kristina, Chen, Yang, Koripella, Ravi Kiran, Mandava, Chandra Sekhar, Sanyal, Suparna, Selmer, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3352095/
https://www.ncbi.nlm.nih.gov/pubmed/22645663
http://dx.doi.org/10.1098/rsob.120016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3352095/
https://www.ncbi.nlm.nih.gov/pubmed/22645663
http://dx.doi.org/10.1098/rsob.120016

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