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Fluorescence properties of the Na(+)/H(+) exchanger inhibitor HMA (5-(N,N-hexamethylene) amiloride) are modulated by intracellular Ph

HMA (5-(N,N-hexamethylene)amiloride), which belongs to a family of novel amiloride derivatives, is one of the most effective inhibitors of Na(+)/H(+) exchangers, while uneffective against Na(+) channels and Na(+)/Ca(2+) exchangers. In this study, we provided evidence that HMA can act as a fluorescen...

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Detalles Bibliográficos
Autores principales: Giansanti, V., Santamaria, G., Torriglia, A., Aredia, F., Scovassi, A.I., Bottiroli, G., Croce, A.C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PAGEPress Publications 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3352132/
https://www.ncbi.nlm.nih.gov/pubmed/22472891
http://dx.doi.org/10.4081/ejh.2012.e3