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Reduced expression of Bax in small cell lung cancer cells is not sufficient to induce cisplatin-resistance

Resistance to cisplatin in the course of chemotherapy contributes to the poor prognosis of small cell lung cancer (SCLC). B cell lymphoma-2 is the founding member of a large family of proteins that either promote or inhibit apoptosis. We aimed at investigating if the pro-apoptotic members Bad, Bax,...

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Detalles Bibliográficos
Autores principales: Biagosch, J, Huber, RM, Bergner, A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3352188/
https://www.ncbi.nlm.nih.gov/pubmed/21156403
http://dx.doi.org/10.1186/2047-783X-15-10-448