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Differential p38-dependent signalling in response to cellular stress and mitogenic stimulation in fibroblasts

p38 MAP kinase is known to be activated by cellular stress finally leading to cell cycle arrest or apoptosis. Furthermore, a tumour suppressor role of p38 MAPK has been proposed. In contrast, a requirement of p38 for proliferation has also been described. To clarify this paradox, we investigated str...

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Detalles Bibliográficos
Autores principales: Faust, Dagmar, Schmitt, Christina, Oesch, Franz, Oesch-Bartlomowicz, Barbara, Schreck, Ilona, Weiss, Carsten, Dietrich, Cornelia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3352310/
https://www.ncbi.nlm.nih.gov/pubmed/22404972
http://dx.doi.org/10.1186/1478-811X-10-6