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Glycogen Synthase Kinase-3β, NF-κB Signaling, and Tumorigenesis of Human Osteosarcoma

BACKGROUND: Glycogen synthase kinase-3β (GSK-3β), a serine/threonine protein kinase, may function as a tumor suppressor or an oncogene, depending on the tumor type. We sought to determine the biological function of GSK-3β in osteosarcoma, a rare pediatric cancer for which the identification of new t...

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Detalles Bibliográficos
Autores principales: Tang, Qing-Lian, Xie, Xian-Biao, Wang, Jin, Chen, Qiong, Han, An-Jia, Zou, Chang-Ye, Yin, Jun-Qiang, Liu, Da-Wei, Liang, Yi, Zhao, Zhi-Qiang, Yong, Bi-Cheng, Zhang, Ru-Hua, Feng, Qi-Sheng, Deng, Wu-Guo, Zhu, Xiao-Feng, Zhou, Binhua P., Zeng, Yi-Xin, Shen, Jing-Nan, Kang, Tiebang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3352834/
https://www.ncbi.nlm.nih.gov/pubmed/22534782
http://dx.doi.org/10.1093/jnci/djs210