Cargando…

Glycogen Synthase Kinase-3β, NF-κB Signaling, and Tumorigenesis of Human Osteosarcoma

BACKGROUND: Glycogen synthase kinase-3β (GSK-3β), a serine/threonine protein kinase, may function as a tumor suppressor or an oncogene, depending on the tumor type. We sought to determine the biological function of GSK-3β in osteosarcoma, a rare pediatric cancer for which the identification of new t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tang, Qing-Lian, Xie, Xian-Biao, Wang, Jin, Chen, Qiong, Han, An-Jia, Zou, Chang-Ye, Yin, Jun-Qiang, Liu, Da-Wei, Liang, Yi, Zhao, Zhi-Qiang, Yong, Bi-Cheng, Zhang, Ru-Hua, Feng, Qi-Sheng, Deng, Wu-Guo, Zhu, Xiao-Feng, Zhou, Binhua P., Zeng, Yi-Xin, Shen, Jing-Nan, Kang, Tiebang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2012
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3352834/ https://www.ncbi.nlm.nih.gov/pubmed/22534782 http://dx.doi.org/10.1093/jnci/djs210

Ejemplares similares

Glycogen synthase kinase 3β in tumorigenesis and oncotherapy
por: He, Rui, et al.
Publicado: (2020)

Enrichment of osteosarcoma stem cells by chemotherapy
por: Tang, Qing-Lian, et al.
Publicado: (2011)

Production of proinflammatory mediators in activated microglia is synergistically regulated by Notch-1, glycogen synthase kinase (GSK-3β) and NF-κB/p65 signalling
por: Cao, Qiong, et al.
Publicado: (2017)

Fine-tuning of NFκB by Glycogen Synthase Kinase 3β directs the fate of glomerular podocytes upon injury
por: Bao, Hui, et al.
Publicado: (2015)

Glycogen Synthase Kinase-3
por: Crouch, Peter, et al.
Publicado: (2011)

Control of Glycogen Content in Retina: Allosteric Regulation of Glycogen Synthase
por: Osorio-Paz, Ixchel, et al.
Publicado: (2012)

Glycogen overload transforms the liver: Accumulated glycogen drives liver tumorigenesis
por: Li, Peiyi, et al.
Publicado: (2022)

Efficacy of glycogen synthase kinase-3β targeting against osteosarcoma via activation of β-catenin
por: Shimozaki, Shingo, et al.
Publicado: (2016)

Polarized Regulation of Glycogen Synthase Kinase-3β Is Important for Glioma Cell Invasion
por: Zou, Qifei, et al.
Publicado: (2013)

Association of glycogen synthase kinase-3β with Parkinson’s disease (Review)
por: LI, DA-WEI, et al.
Publicado: (2014)

Glycogen Synthase Kinase 3β inhibits BMSCs Chondrogenesis in Inflammation via the Cross-Reaction between NF-κB and β-Catenin in the Nucleus
por: Wang, Zhenggang, et al.
Publicado: (2022)

YTHDF2 promotes temozolomide resistance in glioblastoma by activation of the Akt and NF‐κB signalling pathways via inhibiting EPHB3 and TNFAIP3
por: Chen, Yu, et al.
Publicado: (2022)

Colon contradictions: NF-κB signaling in intestinal tumorigenesis
por: Fordham, Robert P., et al.
Publicado: (2015)

A screen for transcription factor targets of Glycogen Synthase Kinase-3 highlights an inverse correlation of NFκB and Androgen Receptor Signaling in Prostate Cancer
por: Campa, Victor M., et al.
Publicado: (2014)

Targeting Glycogen Synthase Kinase 3 Beta Regulates CD47 Expression After Myocardial Infarction in Rats via the NF-κB Signaling Pathway
por: Xu, Li-Na, et al.
Publicado: (2021)

Glycogen synthase kinase GSK3α promotes tumorigenesis by activating HIF1/VEGFA signaling pathway in NSCLC tumor
por: Cao, Xiaonian, et al.
Publicado: (2022)

Mechanism of glycogen synthase inactivation and interaction with glycogenin
por: Marr, Laura, et al.
Publicado: (2022)

Interactomes of Glycogen Synthase Kinase-3 Isoforms
por: Cormier, Kevin W., et al.
Publicado: (2023)

Inflammation, cytokines, the IL-17/IL-6/STAT3/NF-κB axis, and tumorigenesis
por: Chen, Xiao-Wu, et al.
Publicado: (2015)

Glycogen synthase kinase 3β promotes osteosarcoma invasion and migration via regulating PTEN and phosphorylation of focal adhesion kinase
por: Mai, Wei, et al.
Publicado: (2021)

Hexokinase 2, Glycogen Synthase and Phosphorylase Play a Key Role in Muscle Glycogen Supercompensation
por: Irimia, José M., et al.
Publicado: (2012)

Selective growth inhibition by glycogen synthase kinase-3 inhibitors in tumorigenic HeLa hybrid cells is mediated through NF-κB-dependent GLUT3 expression
por: Watanabe, M, et al.
Publicado: (2012)

Role of Glycogen Synthase Kinase-3 in Interferon-γ-Mediated Immune Hepatitis
por: Chen, Chia-Ling, et al.
Publicado: (2022)

Expression of NF-κB and PTEN in osteosarcoma and its clinical significance
por: Gong, Teng, et al.
Publicado: (2017)

Knockdown of DDX46 Inhibits the Invasion and Tumorigenesis in Osteosarcoma Cells
por: Jiang, Feng, et al.
Publicado: (2017)

Clinicopathological and biological significance of aberrant activation of glycogen synthase kinase-3 in ovarian cancer
por: Fu, Yunfeng, et al.
Publicado: (2014)

Inhibition of Glycogen Synthase II with RNAi Prevents Liver Injury in Mouse Models of Glycogen Storage Diseases
por: Pursell, Natalie, et al.
Publicado: (2018)

The NF-κB Signaling Pathway, the Microbiota, and Gastrointestinal Tumorigenesis: Recent Advances
por: Peng, Chao, et al.
Publicado: (2020)

Role of glycogen synthase kinase-3β inhibitor AZD1080 in ovarian cancer
por: Chen, Shuo, et al.
Publicado: (2016)

Extracellular vesicles in tumorigenesis, metastasis, chemotherapy resistance and intercellular communication in osteosarcoma
por: Liao, Yi, et al.
Publicado: (2023)

Deciphering the Signaling Mechanisms of Osteosarcoma Tumorigenesis
por: Nirala, Bikesh K., et al.
Publicado: (2023)

Glycogen Synthase Kinase-3 in the Etiology and Treatment of Mood Disorders
por: Jope, Richard Scott
Publicado: (2011)

Glycogen Synthase Kinase-3 is an Intermediate Modulator of Serotonin Neurotransmission
por: Polter, Abigail M., et al.
Publicado: (2011)

Glycogen Synthase Kinase-3 Is Required for Efficient Dictyostelium Chemotaxis
por: Teo, Regina, et al.
Publicado: (2010)

The Effects of Glycogen Synthase Kinase-3beta in Serotonin Neurons
por: Zhou, Wenjun, et al.
Publicado: (2012)

Glycogen Synthase Kinase 3β in Cancer Biology and Treatment
por: Domoto, Takahiro, et al.
Publicado: (2020)

Glycogen Synthase Kinase 3: Ion Channels, Plasticity, and Diseases
por: Marosi, Mate, et al.
Publicado: (2022)

The role of glycogen synthase kinase 3 beta in neurodegenerative diseases
por: Yu, Honglu, et al.
Publicado: (2023)

Hypoxia Promotes Glycogen Accumulation through Hypoxia Inducible Factor (HIF)-Mediated Induction of Glycogen Synthase 1
por: Pescador, Nuria, et al.
Publicado: (2010)

A novel mutation in the glycogen synthase 2 gene in a child with glycogen storage disease type 0
por: Soggia, Ana Priscila, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_9k2ug6uvot6u1l2s5l7si0efui