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Biodistribution and pharmacokinetics of a telodendrimer micellar paclitaxel nanoformulation in a mouse xenograft model of ovarian cancer

BACKGROUND: A multifunctional telodendrimer-based micelle system was characterized for delivery of imaging and chemotherapy agents to mouse tumor xenografts. Previous optical imaging studies demonstrated qualitatively that these classes of nanoparticles, called nanomicelles, preferentially accumulat...

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Detalles Bibliográficos
Autores principales: Xiao, Wenwu, Luo, Juntao, Jain, Teesta, Riggs, John W, Tseng, Harry P, Henderson, Paul T, Cherry, Simon R, Rowland, Douglas, Lam, Kit S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3352867/
https://www.ncbi.nlm.nih.gov/pubmed/22605931
http://dx.doi.org/10.2147/IJN.S29306