Targeting Cx43 and N-Cadherin, Which Are Abnormally Upregulated in Venous Leg Ulcers, Influences Migration, Adhesion and Activation of Rho GTPases

BACKGROUND: Venous leg ulcers can be very hard to heal and represent a significant medical need with no effective therapeutic treatment currently available. PRINCIPAL FINDINGS: In wound edge biopsies from human venous leg ulcers we found a striking upregulation of dermal N-cadherin, Zonula Occludens...

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Detalles Bibliográficos
Autores principales: Mendoza-Naranjo, Ariadna, Cormie, Peter, Serrano, Antonio E., Hu, Rebecca, O'Neill, Shay, Wang, Chiuhui Mary, Thrasivoulou, Christopher, Power, Kieran T., White, Alexis, Serena, Thomas, Phillips, Anthony R. J., Becker, David L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3352877/
https://www.ncbi.nlm.nih.gov/pubmed/22615994
http://dx.doi.org/10.1371/journal.pone.0037374

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3352877/
https://www.ncbi.nlm.nih.gov/pubmed/22615994
http://dx.doi.org/10.1371/journal.pone.0037374

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