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Reduced Mature MicroRNA Levels in Association with Dicer Loss in Human Temporal Lobe Epilepsy with Hippocampal Sclerosis

Hippocampal sclerosis (HS) is a common pathological finding in patients with temporal lobe epilepsy (TLE) and is associated with altered expression of genes controlling neuronal excitability, glial function, neuroinflammation and cell death. MicroRNAs (miRNAs), a class of small non-coding RNAs, func...

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Detalles Bibliográficos
Autores principales: McKiernan, Ross C., Jimenez-Mateos, Eva M., Bray, Isabella, Engel, Tobias, Brennan, Gary P., Sano, Takanori, Michalak, Zuzanna, Moran, Catherine, Delanty, Norman, Farrell, Michael, O’Brien, Donncha, Meller, Robert, Simon, Roger P., Stallings, Raymond L., Henshall, David C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3352899/
https://www.ncbi.nlm.nih.gov/pubmed/22615744
http://dx.doi.org/10.1371/journal.pone.0035921