BMP-2 Up-Regulates PTEN Expression and Induces Apoptosis of Pulmonary Artery Smooth Muscle Cells under Hypoxia

AIM: To investigate the role of bone morphogenetic protein 2 (BMP-2) in regulation of phosphatase and tensin homologue deleted on chromosome ten (PTEN) and apoptosis of pulmonary artery smooth muscle cells (PASMCs) under hypoxia. METHODS: Normal human PASMCs were cultured in growth medium (GM) and t...

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Detalles Bibliográficos
Autores principales: Pi, Weifeng, Guo, Xuejun, Su, Liping, Xu, Weiguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3352904/
https://www.ncbi.nlm.nih.gov/pubmed/22615735
http://dx.doi.org/10.1371/journal.pone.0035283

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3352904/
https://www.ncbi.nlm.nih.gov/pubmed/22615735
http://dx.doi.org/10.1371/journal.pone.0035283

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