MiR-200c Regulates Noxa Expression and Sensitivity to Proteasomal Inhibitors

The pro-apoptotic p53 target Noxa is a BH3-only protein that antagonizes the function of selected anti-apoptotic Bcl-2 family members. While much is known regarding the transcriptional regulation of Noxa, its posttranscriptional regulation remains relatively unstudied. In this study, we therefore in...

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Detalles Bibliográficos
Autores principales: Lerner, Mikael, Haneklaus, Moritz, Harada, Masako, Grandér, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3352905/
https://www.ncbi.nlm.nih.gov/pubmed/22615771
http://dx.doi.org/10.1371/journal.pone.0036490

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3352905/
https://www.ncbi.nlm.nih.gov/pubmed/22615771
http://dx.doi.org/10.1371/journal.pone.0036490

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