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MiR-200c Regulates Noxa Expression and Sensitivity to Proteasomal Inhibitors
The pro-apoptotic p53 target Noxa is a BH3-only protein that antagonizes the function of selected anti-apoptotic Bcl-2 family members. While much is known regarding the transcriptional regulation of Noxa, its posttranscriptional regulation remains relatively unstudied. In this study, we therefore in...
Autores principales: | Lerner, Mikael, Haneklaus, Moritz, Harada, Masako, Grandér, Dan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3352905/ https://www.ncbi.nlm.nih.gov/pubmed/22615771 http://dx.doi.org/10.1371/journal.pone.0036490 |
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