α-Synuclein Genetic Variants Predict Faster Motor Symptom Progression in Idiopathic Parkinson Disease

Currently, there are no reported genetic predictors of motor symptom progression in Parkinson’s disease (PD). In familial PD, disease severity is associated with higher α-synuclein (SNCA) expression levels, and in postmortem studies expression varies with SNCA genetic variants. Furthermore, SNCA is...

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Detalles Bibliográficos
Autores principales: Ritz, Beate, Rhodes, Shannon L., Bordelon, Yvette, Bronstein, Jeff
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3352914/
https://www.ncbi.nlm.nih.gov/pubmed/22615757
http://dx.doi.org/10.1371/journal.pone.0036199

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3352914/
https://www.ncbi.nlm.nih.gov/pubmed/22615757
http://dx.doi.org/10.1371/journal.pone.0036199

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