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Functional Analysis of Conserved Motifs in Influenza Virus PB1 Protein

The influenza virus RNA polymerase complex is a heterotrimer composed of the PB1, PB2, and PA subunits. PB1, the catalytic core and structural backbone of the polymerase, possesses four highly conserved amino acid motifs that are present among all viral RNA-dependent RNA polymerases. A previous stud...

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Detalles Bibliográficos
Autores principales: Chu, Caroline, Fan, Shufang, Li, Chengjun, Macken, Catherine, Kim, Jin Hyun, Hatta, Masato, Neumann, Gabriele, Kawaoka, Yoshihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3352917/
https://www.ncbi.nlm.nih.gov/pubmed/22615752
http://dx.doi.org/10.1371/journal.pone.0036113