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Tks5-dependent formation of circumferential podosomes/invadopodia mediates cell–cell fusion

Osteoclasts fuse to form multinucleated cells during osteoclastogenesis. This process is mediated by dynamic rearrangement of the plasma membrane and cytoskeleton, and it requires numerous factors, many of which have been identified. The underlying mechanism remains obscure, however. In this paper,...

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Detalles Bibliográficos
Autores principales: Oikawa, Tsukasa, Oyama, Masaaki, Kozuka-Hata, Hiroko, Uehara, Shunsuke, Udagawa, Nobuyuki, Saya, Hideyuki, Matsuo, Koichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3352951/
https://www.ncbi.nlm.nih.gov/pubmed/22584907
http://dx.doi.org/10.1083/jcb.201111116