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Fascin promotes filopodia formation independent of its role in actin bundling

Fascin is an evolutionarily conserved actin-binding protein that plays a key role in forming filopodia. It is widely thought that this function involves fascin directly bundling actin filaments, which is controlled by an N-terminal regulatory serine residue. In this paper, by studying cellular proce...

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Detalles Bibliográficos
Autores principales: Zanet, Jennifer, Jayo, Asier, Plaza, Serge, Millard, Tom, Parsons, Maddy, Stramer, Brian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3352952/
https://www.ncbi.nlm.nih.gov/pubmed/22564415
http://dx.doi.org/10.1083/jcb.201110135