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miR-34s inhibit osteoblast proliferation and differentiation in the mouse by targeting SATB2

A screen of microRNAs preferentially expressed in osteoblasts identified members of the miR-34 family as regulators of osteoblast proliferation and/or differentiation. Osteoblast-specific gain- and loss-of-function experiments performed in vivo revealed that miR-34b and -c affected skeletogenesis du...

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Detalles Bibliográficos
Autores principales: Wei, Jianwen, Shi, Yu, Zheng, Lihua, Zhou, Bin, Inose, Hiroyuki, Wang, Ji, Guo, X. Edward, Grosschedl, Rudolf, Karsenty, Gerard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3352956/
https://www.ncbi.nlm.nih.gov/pubmed/22564414
http://dx.doi.org/10.1083/jcb.201201057