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miR-34s inhibit osteoblast proliferation and differentiation in the mouse by targeting SATB2
A screen of microRNAs preferentially expressed in osteoblasts identified members of the miR-34 family as regulators of osteoblast proliferation and/or differentiation. Osteoblast-specific gain- and loss-of-function experiments performed in vivo revealed that miR-34b and -c affected skeletogenesis du...
Autores principales: | Wei, Jianwen, Shi, Yu, Zheng, Lihua, Zhou, Bin, Inose, Hiroyuki, Wang, Ji, Guo, X. Edward, Grosschedl, Rudolf, Karsenty, Gerard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3352956/ https://www.ncbi.nlm.nih.gov/pubmed/22564414 http://dx.doi.org/10.1083/jcb.201201057 |
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