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Fine-Tuning of Mast Cell Activation by FcεRIβ Chain

Mast cells play a key role in allergic reaction and disorders through the high affinity receptor for IgE (Fc(ε)RI) which is primarily activated by IgE and antigen complex. In humans, mast cells express two types of Fc(ε)RI on the cell surface, tetrameric αβγ(2) and trimeric αγ(2), whereas in mice, t...

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Detalles Bibliográficos
Autores principales: Ra, Chisei, Nunomura, Satoshi, Okayama, Yoshimichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3353146/
https://www.ncbi.nlm.nih.gov/pubmed/22623922
http://dx.doi.org/10.3389/fimmu.2012.00112