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Postnatal liver growth and regeneration are independent of c-myc in a mouse model of conditional hepatic c-myc deletion

BACKGROUND: The transcription factor c-myc regulates genes involved in hepatocyte growth, proliferation, metabolism, and differentiation. It has also been assigned roles in liver development and regeneration. In previous studies, we made the unexpected observation that c-Myc protein levels were simi...

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Detalles Bibliográficos
Autores principales: Sanders, Jennifer A, Schorl, Christoph, Patel, Ajay, Sedivy, John M, Gruppuso, Philip A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3353165/
https://www.ncbi.nlm.nih.gov/pubmed/22397685
http://dx.doi.org/10.1186/1472-6793-12-1