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The NAMPT inhibitor FK866 reverts the damage in spinal cord injury

BACKGROUND: Emerging data implicate nicotinamide phosphoribosyl transferase (NAMPT) in the pathogenesis of cancer and inflammation. NAMPT inhibitors have proven beneficial in inflammatory animal models of arthritis and endotoxic shock as well as in autoimmune encephalitis. Given the role of inflamma...

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Detalles Bibliográficos
Autores principales: Esposito, Emanuela, Impellizzeri, Daniela, Mazzon, Emanuela, Fakhfouri, Gohar, Rahimian, Reza, Travelli, Cristina, Tron, Gian Cesare, Genazzani, Armando A, Cuzzocrea, Salvatore
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3353188/
https://www.ncbi.nlm.nih.gov/pubmed/22490786
http://dx.doi.org/10.1186/1742-2094-9-66