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Interleukin-1 participates in the classical and alternative activation of microglia/macrophages after spinal cord injury

BACKGROUND: Microglia and macrophages (MG/MΦ) have a diverse range of functions depending on unique cytokine stimuli, and contribute to neural cell death, repair, and remodeling during central nervous system diseases. While IL-1 has been shown to exacerbate inflammation, it has also been recognized...

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Detalles Bibliográficos
Autores principales: Sato, Atsushi, Ohtaki, Hirokazu, Tsumuraya, Tomomi, Song, Dandan, Ohara, Kenji, Asano, Masahide, Iwakura, Yoichiro, Atsumi, Takashi, Shioda, Seiji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3353190/
https://www.ncbi.nlm.nih.gov/pubmed/22483094
http://dx.doi.org/10.1186/1742-2094-9-65