Characterization of the transcriptome profiles related to globin gene switching during in vitro erythroid maturation

BACKGROUND: The fetal and adult globin genes in the human β-globin cluster on chromosome 11 are sequentially expressed to achieve normal hemoglobin switching during human development. The pharmacological induction of fetal γ-globin (HBG) to replace abnormal adult sickle β(S)-globin is a successful s...

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Detalles Bibliográficos
Autores principales: Li, Biaoru, Ding, Lianghao, Li, Wei, Story, Michael D, Pace, Betty S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3353202/
https://www.ncbi.nlm.nih.gov/pubmed/22537182
http://dx.doi.org/10.1186/1471-2164-13-153

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3353202/
https://www.ncbi.nlm.nih.gov/pubmed/22537182
http://dx.doi.org/10.1186/1471-2164-13-153

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