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Tetrathiomolybdate sensitizes ovarian cancer cells to anticancer drugs doxorubicin, fenretinide, 5-fluorouracil and mitomycin C

BACKGROUND: Our recent study showed that tetrathiomolybdate (TM), a drug to treat copper overload disorders, can sensitize drug-resistant endometrial cancer cells to reactive oxygen species (ROS)-generating anticancer drug doxorubicin. To expand these findings in the present study we explore TM effi...

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Detalles Bibliográficos
Autores principales: Kim, Kyu Kwang, Lange, Thilo S, Singh, Rakesh K, Brard, Laurent, Moore, Richard G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3353246/
https://www.ncbi.nlm.nih.gov/pubmed/22502731
http://dx.doi.org/10.1186/1471-2407-12-147