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Thyroid Hormone-Induced Cytosol-to-Nuclear Translocation of Rat Liver Nrf2 Is Dependent on Kupffer Cell Functioning

L-3,3′,5-triiodothyronine (T(3)) administration upregulates nuclear factor-E2-related factor 2 (Nrf2) in rat liver, which is redox-sensitive transcription factor mediating cytoprotection. In this work, we studied the role of Kupffer cell respiratory burst activity, a process related to reactive oxyg...

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Detalles Bibliográficos
Autores principales:	Videla, Luis A., Cornejo, Pamela, Romanque, Pamela, Santibáñez, Catherine, Castillo, Iván, Vargas, Romina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Scientific World Journal 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3353293/ https://www.ncbi.nlm.nih.gov/pubmed/22649286 http://dx.doi.org/10.1100/2012/301494

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