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The non-invasive (13)C-methionine breath test detects hepatic mitochondrial dysfunction as a marker of disease activity in non-alcoholic steatohepatitis

INTRODUCTION: Mitochondrial dysfunction plays a central role in the general pathogenesis of non-alcoholic fatty liver disease (NAFLD), increasing the risk of developing steatosis and subsequent hepatocellular inflammation. We aimed to assess hepatic mitochondrial function by a non-invasive (13)C-met...

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Detalles Bibliográficos
Autores principales: Banasch, M, Ellrichmann, M, Tannapfel, A, Schmidt, WE, Goetze, O
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3353401/
https://www.ncbi.nlm.nih.gov/pubmed/21810560
http://dx.doi.org/10.1186/2047-783X-16-6-258