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Tautomerism in 11-Hydroxyaklavinone: A DFT Study

The antharquinone-based chromophore of 11-hydroxyaklavinone is present in the structure of an anticancer agent, daunomycin. On the other hand, aklavinone is the parent aglycone of certain anthracycline antibiotics that possess anti-cancer activity too. The structures of aklavinone and its 11-hydroxy...

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Detalles Bibliográficos
Autor principal: Türker, Lemi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Scientific World Journal 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3353482/
https://www.ncbi.nlm.nih.gov/pubmed/22623911
http://dx.doi.org/10.1100/2012/526289