Old flies have a robust central oscillator but weaker behavioral rhythms that can be improved by genetic and environmental manipulations

Sleep–wake cycles break down with age, but the causes of this degeneration are not clear. Using a Drosophila model, we addressed the contribution of circadian mechanisms to this age-induced deterioration. We found that in old flies, free-running circadian rhythms (behavioral rhythms assayed in const...

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Detalles Bibliográficos
Autores principales: Luo, Wenyu, Chen, Wen-Feng, Yue, Zhifeng, Chen, Dechun, Sowcik, Mallory, Sehgal, Amita, Zheng, Xiangzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2012
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3353743/
https://www.ncbi.nlm.nih.gov/pubmed/22268765
http://dx.doi.org/10.1111/j.1474-9726.2012.00800.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3353743/
https://www.ncbi.nlm.nih.gov/pubmed/22268765
http://dx.doi.org/10.1111/j.1474-9726.2012.00800.x

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