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Old flies have a robust central oscillator but weaker behavioral rhythms that can be improved by genetic and environmental manipulations
Sleep–wake cycles break down with age, but the causes of this degeneration are not clear. Using a Drosophila model, we addressed the contribution of circadian mechanisms to this age-induced deterioration. We found that in old flies, free-running circadian rhythms (behavioral rhythms assayed in const...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Blackwell Publishing Ltd
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3353743/ https://www.ncbi.nlm.nih.gov/pubmed/22268765 http://dx.doi.org/10.1111/j.1474-9726.2012.00800.x |