A Potent, Versatile Disulfide-Reducing Agent from Aspartic Acid

[Image: see text] Dithiothreitol (DTT) is the standard reagent for reducing disulfide bonds between and within biological molecules. At neutral pH, however, >99% of DTT thiol groups are protonated and thus unreactive. Herein, we report on (2S)-2-amino-1,4-dimercaptobutane (dithiobutylamine or DTB...

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Detalles Bibliográficos
Autores principales: Lukesh, John C., Palte, Michael J., Raines, Ronald T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2012
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3353773/
https://www.ncbi.nlm.nih.gov/pubmed/22353145
http://dx.doi.org/10.1021/ja211931f

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3353773/
https://www.ncbi.nlm.nih.gov/pubmed/22353145
http://dx.doi.org/10.1021/ja211931f

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