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A Potent, Versatile Disulfide-Reducing Agent from Aspartic Acid
[Image: see text] Dithiothreitol (DTT) is the standard reagent for reducing disulfide bonds between and within biological molecules. At neutral pH, however, >99% of DTT thiol groups are protonated and thus unreactive. Herein, we report on (2S)-2-amino-1,4-dimercaptobutane (dithiobutylamine or DTB...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3353773/ https://www.ncbi.nlm.nih.gov/pubmed/22353145 http://dx.doi.org/10.1021/ja211931f |